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Inflammatory chemokine transport and presentation in HEV: a remote control mechanism for monocyte recruitment to lymph nodes in inflamed tissues

however, excessive dosing may result in exaggerated pharmacological effects

Int J Radiat Oncol Biol Phys 95(4):1117-31, 2016

Interestingly, the inability of CD8 + T cells to deal with excessive intracellular ammonia, originating from glutaminolysis, leads to mitochondrial and lysosomal damage and cell death

The cost of the procedure itself, as well as the pellets, can be a significant financial burden, especially considering that they need to be replaced periodically