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Description

A key molecular target for treatment of schizophrenia is the N-methyl-D-aspartate (NMDA) receptor, a glutamate receptor and ion channel in neurons, which appears to be modulated by NAC

One such pathway, identified later, is the FSP1 pathway

Systemic delivery of Small Interfering RNA Therapeutics: Obstacles and advances

This pathway typically suppresses NF-B activation and NLRP3 inflammasome activity, leading to reduced production of key pro-inflammatory cytokines (e.g., TNF-, IL-6, IL-12) by macrophages and DCs (98)