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L'histidine de la triade catalytique est situe l'extrmit carboxy-terminale du dernier brin du feuillet constituant le repliement / tandis que l'acide carboxylique est gnralement situ l'extrmit du 7 e brin, sauf pour la lipase pancratique o il est situ l'extrmit du 6 e brin (Derewenda et al., 1992

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