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CSF-derived cfDNA has recently been applied in clinical practice for analysis of BM, including being used to guide treatment decisions [46]

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The most defensible statement is narrow: severe deficiency of methionine and choline impairs hepatic fat export and causes steatosis the classic methionine-choline-deficient (MCD) diet reliably induces fibrosing steatohepatitis in rodents [4] [5]

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Further, molecular and biochemical reagents to study tree shrews have not been well characterized

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It also mitigates mast cell activity [160] and angiogenesis via VEGF and EDN-1 inhibition [172, 173]

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