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Immune-modulating agent therapy may be therapeutically beneficial for patients with immune dysregulation

Traumatic brain injuryrelated emergency department visits, hospitalizations, and deathsUnited States, 2007 and 2013

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Echinocandins are largely ineffective against Cryptococcus , and the efficacy of other agents is often compromised by host toxicity or fungal resistance (Denning, 2003) ( Supplementary File 1 )