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86 In the final step, catalyzed by -keto thiolase, the - carbon bond is broken, resulting in the formation of acetyl-CoA and a shortened fatty acyl-CoA, allowing the cycle to repeat until all even-chain fatty acids are converted into acetyl-CoA

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A study employing high-resolution immunocytochemistry at both light and electron microscopic levels in rodents has demonstrated that neurons efficiently uptake lactate via monocarboxylate transporter 2 (MCT2), a high-affinity transporter localized at postsynaptic densities to facilitate lactate import from astrocyte-released sources (Bergersen, 2007) and subsequently convert it to pyruvate via lactate dehydrogenase isotype 1