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heteroaryl groups include thienyl, imadizolyl, oxadiazolyl, isoxazolyl, triazolyl, pyridyl, pyrimidinyl, pyridazinyl, furyl, pyranyl, thianthrenyl, pyrazolyl, pyrazinyl, indolizinyl, isoindolyl, isobenzofuranyl, benzoxazolyl, xanthenyl, 2H-pyrrolyl, pyrrolyl, 3H-indolyl, indolyl, indazolyl, purinyl, 4H-quinolizinyl, isoquinolyl, quinolyl, phthalazinyl, naphthyridinyl, quinazolinyl, phenanthridinyl, acridinyl, perimidinyl, phenanthrolinyl, phenazinyl, isothiazolyl heteroaryl groups include 1,2,3-triazole, 1,2,4-triazole, 5-amino 1,2,4-triazole, imidazole, oxazole, isoxazole, 1,2,3-oxadiazole, 1,2,4-oxadiazole, 3-amino-1,2,4-oxadiazole, 1,2,5-oxadiazole, 1,3,4-oxadiazole, pyridine, and 2-aminopyridine

Most gastrointestinal symptoms are dose-dependent and typically resolve within the first few weeks of treatment

(99) demonstrated that adipocytes mediate drug resistance in MM plasma cells, contributing to recurrence and/or disease progression (99)

After 2 months, 1 ampoule (0.5 mg of B 29 AQ PFS INJECTION 1 ML) is given every one to three months as a part of maintenance therapy

Healthcare providers do this by going through the patients medical history to understand the requirement, the patients condition and treatment plan