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These materials can also be processed into nano-sized particles, which help the materials to improve the bioavailability and stability, and overcome their toxicity

Although several environmental agents are implicated in the pathogenesis of ADs via numerous mechanisms, below we discuss the more prominent ones which are not only known to induce/exacerbate autoimmunity but also have oxidative stress (OS) as one common mechanism, and participate in the pathogenesis of ADs (Figure 1): Figure 1 Mercury Mercury (Hg) is a well-established environmental toxicant and its exposure in humans is associated with markers of inflammation and autoimmunity ( In vivo studies using autoimmune-prone murine models report that exposure to inorganic Hg leads to lupus-like syndrome

Hopkins, R

10.1111/j.13652982.2010.01584.x 52

Certain neurotransmitters like GABA and serotonin produced by gut bacteria, play a vital role in the gut-brain axis