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Additionally, the APOE-4 allele is the strongest genetic risk factor for both early- and late-onset AD, contributing to increased amyloid deposition and disease progression (Kim et al., 2009)

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To assess cell viability, 10 l CellTiter-Fluor (Promega) was added to black plates and incubated for 30 min in the dark before fluorescence was measured at 7-mm depth (gain 100)

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