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Our cross-sectional data support the potential role of mushrooms and their bioactive compounds in delaying neurodegeneration." www.pubmed.ncbi.nlm.nih.gov/30775990/ By contrast, low levels of Ergothioneine have been associated with cognitive decline in aging populations

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Hypoxic stress-induced tumor and immune plasticity, suppression, and impact on tumor heterogeneity

On the other hand, it must be stressed that the above values are averages and there might be significant spatial heterogeneity 57

Roles of the human hypoxia-inducible factor (HIF)-3 variants in the hypoxia response