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Description

Knockdown of GlutamateCysteine Ligase by Small Hairpin RNA Reveals That Both Catalytic and Modulatory Subunits Are Essential for the Survival of Primary Neurons *. Journal of Biological Chemistry 280: 3899239001

2020;63(12):63876406 SYNOPSIS This perspective paper describes how a strategic approach has evolved at Pfizer that utilizes the increasingly pivotal role of biotransformation studies in drug design and development