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Pehar, M., Harlan, B

The decision in the amount of animals used for the study was following the 3Rs (Replacement, Reduction and Refinement) to avoid unnecessary sacrifice

Pathophysiological Mechanisms Underlying Oxidative Stress Free radicals are chemically reactive molecules containing one or more unpaired electrons, such as hydroxyl radical ( OH), superoxide (O 2 ), or nitric oxide ( NO) [9,13]

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