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Consistent with our earlier results, mitochondrial mass was not significantly changed in either control or IGF-1R cKO Th17 cells treated with IGF-1 (Fig

Foundational mechanism paper

The bottom line: mechanistically sound doesn't mean clinically validated

However, results are dose-dependent and more effective when combined with a calorie-controlled diet or exercise program Could Help Prevent Fat Storage (Reduced Lipogenesis) Some animal studies suggest AOD9604 may limit the formation of new fat cells, known as lipogenesis (preclinical evidence)