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Doctors hope enough people get vaccinated to help avert another tripledemic like last year when hospitals were overwhelmed with an early flu season, an onslaught of RSV, or respiratory syncytial virus, and yet another winter coronavirus surge

Intravenous administration of IL-12 encoding self-replicating RNAlipid nanoparticle complex leads to safe and effective antitumor responses

Magalhes-GuedesKBarretoITavaresPBezerraPSilvaMNunesIet al

Zinc-mediated inhibition of cyclic nucleotide phosphodiesterase activity and expression suppresses TNF-alpha and IL-1 beta production in monocytes by elevation of guanosine 3,5-cyclic monophosphate

What is also unknown is the effect on cognition, and any neuroprotective benefit, in younger or healthy individuals remains unknown, some positive results have been reported, 6 however a large scale confirmatory study is still required