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Limb dystonia was associated with hemiataxia, other hyperkinetic movement disorders like chorea, myoclonus [ 48 , 50 ] or ocular motor abnormality [ 51 , 52 ] Dystonia which affects younger adults with significantly high titre usually has a good response to immunotherapy [ 46 ]

ongoing efforts to evaluate therapeutic strategies that target proapoptotic signaling pathways (see Chap

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