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Sharma P, Allison JP

Phelps HA, Kuntz CA, Milner RJ, Powers BE, Bacon NJ (2011): Radical excision with five-centimeter margins for treatment of feline injection-site sarcomas: 91 cases (1998-2002)

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Importantly, next-generation IL-2 variants, such as engineered IL-2R-biased agonists or bispecific PD1targeted interleukin2 variant molecules that avoid CD25 binding, are designed to preferentially expand memory-like or stem-like tumor-reactive CD8 T cells while modulating the exhaustion program and reprogramming the immunosuppressive TME [234, 244, 327,328,329,330,331]