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Uncropped scans of fluorescent gels and gels stained with Coomassie blue are provided in Supplementary Figs

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Ashwagandha sometimes is better tolerated (it works more on GABA and cortisol), but some slow COMT individuals even find ashwagandha stimulating or too much. Ginseng (especially Panax ginseng) can raise dopamine and adrenalinelikely not ideal for slow COMT

COG, clusters of orthologous groups

Skin benefits : Reduces fine lines and wrinkles Improves skin thickness Enhances firmness and elasticity Evens skin tone Reduces hyperpigmentation Promotes healing of scars and damage Improves texture Mechanisms : Stimulates collagen I and III production Promotes elastin synthesis Enhances hyaluronic acid Improves blood flow to skin Antioxidant protection Protocol : Topical : Apply serum/cream 2x daily Injectable : 1-2mg daily subcutaneous Expected results : Visible improvement in 8-12 weeks, significant changes by 6 months