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Innovation in Dual and Triple Agonist Therapies The fact that Cagrilintide and Semaglutide work well together supports the dual-agonist approach and encourages the creation of molecules that combine multiple receptor functions within a single peptide structure

2021, doi: 10.1016/S0140-6736(21)01751-7

To date, no severe adverse effects have been consistently documented in research settings

SURMOUNT-2 investigators

Reconstitution Math Vial contents: 5 mg cagrilintide + 5 mg Semaglutide = 10 mg total blend Add: 3.0 mL bacteriostatic water Concentration: 10 mg 3.0 mL = 3.33 mg/mL total (1.67 mg/mL each peptide) Per unit (U100 syringe): 3333 mcg/mL 0.01 mL = 33.3 mcg total per unit (16.7 mcg each peptide) Reconstitution Steps Draw 3.0 mL bacteriostatic water with a sterile syringe