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however, kinetic data indicate a higher activity rate of jr PPO1-wt with L -DOPA ( k cat = 111.2 s 1 ) than with dopamine ( k cat = 92.5 s 1 )

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These findings indicated that the combination of (-)-Vestitol and Salviolone had synergistic effects on reducing both the A plaque burden and toxic soluble A levels in the cortex and hippocampus of APP/PS1 transgenic mice