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We therefore propose that tissue-associated oxidative stress may promote conversion of circulating TTR into dsNNTTR locally within the interstitial compartment, rather than exclusively during intracellular synthesis or processing

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Immunofluorescence (IF) was also performed on liver tissues for -catenin pathway and proliferation analysis

E, K, B5, B6, and B9 vitamins and their specific immunological effects evaluated by flow cytometry