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Description

Efficacy and safety of leriglitazone in patients with Friedreich ataxia: a phase 2 double-blind, randomized controlled trial (FRAMES)

10.3390/nu11092090 143 ShaW.ZhaoB.WeiH.YangY.YinH.GaoJ.et al (2023)

By strengthening the intestinal barrier through SCFA-dependent mechanisms, including upregulation of tight junction proteins via AMPK activation and HIF stabilization (Guo et al., 2021