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Vitamin B 12 is needed to prevent anemia, since making porphyrin and heme in mitochondria for producing hemoglobin in red blood cells depends on succinyl-CoA made by vitamin B 12

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A repeated-measures two-way ANOVA revealed a significant main effect of the factors treatment (F(1,16)=12.47, P=0.0028), time (days) (F(5,80)=4.437, P=0.0012), and a significant treatment x time interaction (F(5,80)=10.89, P 0.05;FIG