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Zhou, B., Yang, Y

J Neurol Neurosurg Psychiatry 2000;68:690

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Recombinant CYP1A2 and CYP3A4 including a microsomal formulation containing cytochrome b 5 and cytochrome P450 reductase, drug-metabolizing cytochromes P450, interacted with wild-type PGRMC1, but not with the Y113F mutant, in a haem-dependent manner (Fig

Recent evidence leans towards an integrated model in which autoimmunity, mediated mainly by cytotoxic T lymphocytes and inflammatory cytokines, plays a central role