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GPX4 consumes GSH to reduce lipid hydroperoxides (L-OOH) to lipid alcohols

Assay Testing Assay testing verifies peptide content, concentration, and label accuracy for finished formulations such as capsules and sprays

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The method is based on the assumption, that the binding of the (pro)drug occurs mainly inside the cells and that estimation of C u,cell indicates the overall unbound drug concentration in the brain intracellular compartment without specifying the distribution to the specific parenchymal cells or subcellular structures