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Studies have demonstrated that the abnormal aggregation of -syn is a significant trigger of neuroinflammation in PD (Park et al., 2021)

Neuromodulatory systems constitute key therapeutic targets for cognitive enhancement [223]

The selectivity advantage is well-supported in animal data and is pharmacologically plausible in humans, but the claim that Ipamorelin does not raise cortisol in humans is extrapolating from rat data rather than reporting a confirmed human finding