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PFTs were performed only in subjects five years of age and older (n = 24), thus limiting the power to observe any relationship with treatment

Recent studies have identified over 100 genetic loci associated with migraines, which impact neurotransmission, inflammatory responses, and pain perception (Grangeon et al., 2023)

Instead, ALA may work best as a complementary therapy alongside standard treatments and lifestyle changes

People with metabolic diseases, such as metabolic syndrome, type 2 diabetes, and metabolic dysfunction-associated steatotic liver disease (formerly NAFLD), [can also benefit from it] since ALCAR can support fatty acid metabolism, Warner adds

Transcriptomic comparisons between FA- and estrogen-treated cells revealed upregulation of genes involved in energy metabolism, particularly those related to ATP regeneration