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Furthermore, we focus on the role of protein glutathionylation recently found in fused-in-sarcoma (FUS)-associated ALS and discuss whether this glutathionylation has a pathological role in the development and progression of ALS by modulating LLPS of RBPs, particularly FUS

Gene 668 , 4853 (2018)

He, F., Ru, X., & Wen, T

It will be essential in future studies to explore these mechanisms and to determine the role of other binding partners of BRD4 and ASXL1 in the formation of the BRD4-ASXL1 complex

This work should be viewed as a proof of concept that demonstrates the feasibility of the approach rather than evidence of efficacy