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The ocean is a special environment with high pressure, high salinity, low temperature and weak illumination, but with local high temperature and high ultraviolet radiation in the ocean surface

Since acute ethanol consumption and riboflavin deficiency each induces oxidative stress within tissues

"Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration"

Notably, the cystine/cysteine-involved ferroptosis pathway has been extensively studied

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