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10.3390/life10070101 Life 3 AlbrechtJ.ZieliskaM

Am J Physiol Cell Physiol 294:13051312

MSC-EVs function predominantly by the activation of autophagy via the catalase enzyme, the Nrf2 signalling pathway, the miR 146a-inhibited NF-B pathway, and the targeting of the PTEN-PI3 K/Akt pathway by miR-223 (145)

Conclusion: In this meta-analysis, psychosocial intervention alone was not statistically significant in reducing alcohol return to drinking when compared to the standard of care in patients with CLD with AUD