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Ask what symptoms should be evaluated first, whether labs or stool testing are appropriate, what the research actually supports, what is still unknown, how safety would be monitored, and how progress would be measured

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IGF-1 activates multiple signaling pathways in bone cells including the PI3K/Akt pathway, which promotes osteoblast survival and function, and the MAPK pathway, which enhances collagen and non-collagenous protein synthesis

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