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This may reflect the combined impact of lower baseline estrogen and progesterone, plus reduced GI sensitivity

J Clin Endocrinol Metab 2011;96:150-158

Tryptophan increased serum 5-HT levels, enhanced brain BDNF expression, reduced neuroinflammation, improved mitochondrial energy metabolism and restored gut barrier integrity by upregulating tight junction proteins (Weng et al., 2024

Then reinsert the needle and syringe an inch or so away from where it was before

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