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Carcinomatous changes in an area of chronic ulceration, or Marjolins ulcer

Arandjelovic S, Perry JSA, Lucas CD, Penberthy KK, Kim T-H, Zhou M, et al

have shown that carbon monoxide-releasing molecule (CORM)-2 causes the upregulation of HO-1, which inhibits thioredoxin-interacting protein (TXNIPrx)/NLR family pyrin domain-containing 3 (NLRP3) inflammasome pathway in LPS-induced acute lung injury [122]

For example, exposure to artificial light at night can impact biological processes and have pathological consequences, whereas artificial light exposure during the day would not have the same effect [12]