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Description

EMBO Journal 16, 62096216

10.3389/fncel.2018.00472 24 HabibE.Linher-MelvilleK.LinH

Subclinical and overt B 12 deficiency may be easily overlooked in the elderly population since clinical signs are absent or nonspecific, laboratory biomarkers may be influenced by reduced kidney function, and B 12 absorption is impaired by reduced gastric acidity, e.g., due to proton-pump inhibitors or other drugs, e.g., metformin