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The Court for Arbitration for Sport began hearing an appeal by the World Anti-Doping Agency (WADA) against the tribunal's ruling earlier this month

In this context, it is noteworthy that ibuprofen is known to reduce inflammation via inhibition of COX-2, but also via modulation of the angiotensin pathway by shifting the ACE/ACE-2 (angiotensin converting enzyme) receptor ratio towards ACE-2 (119, 120) (discussed in detail in Section 4.2)