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The sooner your treatments start, the less progress we have to reverse

doi: 10.1007/s10815-006-9084-7 187 MakhlufSBAbu-MukhRRubinsteinSBreitbartHGedankenA

In the terminal ileum, the intrinsic factor-Cbl complex ( Cbl/IF ) binds to IF receptors (a receptor composed of a heterodimer of amnionless and cubilin , called cubam ) on the apical surface of ileal enterocytes and is then transferred through the ileal membrane by endocytosis