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Using a kinetic assay, the amount of total glutathione was determined by continuously reducing 5,5-dithiobis (2-nitrobenzoic acid) (Sigma-Aldrich) to 5-thio-2-nitrobenzoic acid in the presence of catalytic amount (nmol) of GSH (TNB), and GSH reductase and nicotinamide adenine dinucleotide phosphate (Sigma-Aldrich) regenerated the GSSG (oxidized GSH) that was produced

Mendez, 2019

We compared patients seen by the ALivE service (intervention) at Massachusetts General Hospital to those who received standard of care at our neighboring, tertiary-care hospital (Brigham and Womens Hospital) over the same time period of 2020-2024

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(senior investigator and chief, Genetic Epidemiology Research Branch, NIMH), has devoted substantial effort to characterizing the prevalence and correlates of sleep patterns and disorders in both general population samples and a local community-based family cohort of more than 1,000 individuals