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Capmatinib can inhibit phosphorylation of c-MET as well as c-MET pathway downstream effectors such as ERK1/2, AKT, FAK, GAB1, and STAT3/5

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That means three things in practice

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Interestingly, metronidazole gel has been found to be effective in SD and could be trialled in this case in the future if needed

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[] In this case, despite three surgeries and prolonged local wound care, the abdominal incision failed to close spontaneously, requiring a definitive fistula resection

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Available from: [DOI] [PubMed] [Google Scholar] 163.Gleadle JM, Ebert BL, Firth JD, Ratcliffe PJ

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