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The findings were also reflected in a decreased co-localization of mitotracker and lysotracker following treatment with 3-methyl adanine and increased co-localization of mitotracker and lysotracker by rapamycin treatment (Taki et al., 2020)

La rduction de l'indice de mlanine tait statistiquement significative par rapport au placebo dans la majorit des essais, mais les auteurs ont conclu que les limites mthodologiques principalement la petite taille des cohortes et l'absence de donnes long terme ne permettaient pas de considrer l'effet claircissant comme bien tabli