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Accumulating evidence suggests a connection between the inflammatory response and aberrant activation of the cGAS-STING pathway [61]

The molecular architectures of various lipids, such as fatty acids, cholesterol, terpenes, and phospholipids, are fundamentally distinct, indicating differences in linkage modalities between lipids and proteins

While some studies suggest that such cells may retain certain regulatory functions, others indicate that they can adopt a pathogenic role ( 2.1.2 Regulation of cytokine signaling Th17 and Treg cells' differentiation paths are determined by the cytokine microenvironment, an extrinsic factor ( The induction of non-pathogenic Th17 cells under homeostatic conditions, which are characterized by the expression of genes like Il10, requires low concentrations of TGF- in conjunction with IL-6