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Potential Side Effects: Gastrointestinal effects (most common): nausea, vomiting, diarrhea, constipation, abdominal paintypically mild to moderate and decreasing with gradual dose escalation [1] [3]

A 2025 intravenous safety study involving two healthy adults found infusions up to 20 mg well tolerated, with no adverse events or clinically meaningful changes in vital signs or laboratory biomarkers

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Although children have a higher percentage of detectable antibodies from natural infection than adults, natural immunity on a population level is insufficient in protecting kids, the ACIP said, as natural immunity protection is random and there is no way to protect who will get strong protection and who will get no protection from it

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