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[DOI] [PubMed] [Google Scholar] [26].Hayward MG, Keatinge WR

Its influence on RNA methylation by modulating enzymes such as METTL3, FTO, and YTHDF adds a novel layer to its anticancer profile, demonstrating its capacity to regulate mRNA stability, translation, and gene expression at a post-transcriptional level

Brosnan JT (2000) Glutamate, at the Interface between amino acid and carbohydrate metabolism

it can happen because of many reasons including direct exposure to UV radiation on exposed areas of skin, immunogenic skin problems, DNA damage due to various reasons, skin color, sun tanning bed, and many more