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Unlike dogs and rodents, which lack multiple medullary pyramids and therefore bypass segmental arteries, humans, pigs, and sheep possess a complex system of interlobar and segmental arteries that supply the numerous kidney lobes 12

doi: 10.1016/j.watres.2021.117826 114 HoS-MCheongAAdgentMAVeeversJSuenAATamNNCet al

Upon activation, HSF1 trimers translocate to the nucleus and bind to heat shock elements (HSEs) in the promoters of target genes, thereby increasing the transcription of HSP70s, which then undergo degradation or re-monomerization (Vihervaara and Sistonen, 2014)

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Combining this with other aesthetic procedures, such as laser skin brightening, can achieve better outcomes