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10.1038/s41467-019-08680-6 152

Returning to the subject of glutathione production in the body, this can occur in three different ways

Although not statistically significant, LP-EVs promoted the upregulation of pathways associated with tight junctions and extracellular matrix (ECM) receptor interactions in skin tissues, changes that may also contribute to acne improvement [73, 74] (Figure S9)

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Consequently, ROS damage the different parts of cells, including lipids, proteins and nucleic acid that leads to several chronic and degenerative conditions like aging, dementia, cardiovascular diseases, kidney diseases, neurodegeneration, cancer, respiratory disorder, rheumatoid arthritis as well as several other metabolic ailments [2]