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22(1): 4654 Jiang X, Williams KM, Liauw WS, et al

doi: 10.1038/s41538-024-00348-w 188

PMID: 16 WHO

Only some hopeful sEH inhibitor candidates are subjected now to clinical trials such as GSK2256294A in Phase-I and AR9281 in Phase-II against chronic obstructive pulmonary disease (COPD) and hypertension

When administered orally, up to 23% of individuals experience gastrointestinal problems such as nausea and vomiting, which are the most frequent side effects