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The parallel upregulation of Syn3 , which regulates synaptic vesicle priming and dopaminergic release [85], further supports convergence on disrupted dopaminergic and motivational circuitry

Geriatric use : No overall differences in safety or effectiveness were observed between these subjects and younger subjects, and other reported clinical experience has not identified differences in responses between the elderly and younger patients

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[DOI] [PubMed] [Google Scholar] 96.Steele T.A., St Louis E.K., Videnovic A., Auger R.R