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This would manifest in shortness of breath and chronic tiredness

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Healthcare utilization and costs in diabetes relative to the clinical spectrum of painful diabetic peripheral neuropathy

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Przez przecicie dwch osi metabolizmu nikotynamidu (NAD) i metabolizmu grup metylowych (SAM/SAH) hamowanie NNMT wpywa jednoczenie na dostpno prekursora NAD i na bilans donorw metylowych w komrce