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Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis

Pharmacol Rev (2010) 62(3):40596

Moreover, lactate produced by tumor cells may serve as a key molecule that stimulates CAFs to produce HGF through a nuclear factor-B (NF-B)-dependent mechanism [88, 142, 143], thus promoting a feed-forward pro-survival loop between tumors and TME [41]

Glutathione is a tripeptide amino acid naturally produced in the liver that functions as a powerful cellular antioxidant by inhibiting free radical formation

Substantial lipid aggregation induces activation of pyroptosis signaling pathways in the formation of vulnerable atherosclerotic plaques (123)