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10.1177/20417314221113391 J

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The important distinctions are labeled dosing versus compounded-unit math, escalation and missed-dose rules, measurement errors, tolerability, and the symptoms that should trigger a call to a licensed prescriber

This progression delineates a developmental pathway in iHLOs, transitioning from epithelial-centric populations to a more diverse composition including mesenchymal cell types by Day 45 (Fig