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Mice lacking either TAP-1 (transporter associated with antigen processing 1) or 2 microglobulin, crucial components for MHC-I antigen presentation, display impaired CD8 + T cell responses and succumb more rapidly post- M

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In vitro and animal-based studies have explored AOD-9604's interactions with osteoblast and osteoclast activity, investigating its role in bone remodeling pathways independent of IGF-1 signaling