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5 Using elevated metabolite levels (ie, serum methylmalonic acid [MMA] or homocysteine [Hcy]) to define deficiency, the screening serum B 12 cutoff used in many diagnostic algorithms has been raised to 250 pg/mL to 300 pg/mL to provide greater sensitivity

In clinical practice, a B1-B6-B12 injection may be considered when oral therapy is insufficient or not feasible, such as in malabsorption, severe deficiency, or when accelerated replenishment is desired under medical supervision

PMID: 105 CuolloLDi CristofanoSSandomenicoAIaccarinoEOliverAZingoniAet al

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Q2: What signs suggest a dog or cat may have a Vitamin B12 deficiency